Molecular Mechanisms of Adenosine Stress T1 Mapping
نویسندگان
چکیده
منابع مشابه
Splenic T1-mapping: a novel quantitative method for assessing adenosine stress adequacy for cardiovascular magnetic resonance
BACKGROUND Perfusion cardiovascular magnetic resonance (CMR) performed with inadequate adenosine stress leads to false-negative results and suboptimal clinical management. The recently proposed marker of adequate stress, the "splenic switch-off" sign, detects splenic blood flow attenuation during stress perfusion (spleen appears dark), but can only be assessed after gadolinium first-pass, when ...
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Background Myocardial vasodilator reserve is an important surrogate marker of normal and abnormal cardiac physiology. Pharmacological vasodilator agents such as adenosine increase myocardial blood volume, which is expected to prolong the observed T1-relaxation. We explored the novel application of stress T1-mapping by assessing the response of myocardial T1 to the administration of adenosine in...
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BACKGROUND Myocardial T1 relaxation times have been reported to be markedly abnormal in diverse myocardial pathologies, ascribed to interstitial changes, evaluated by T1 mapping and calculation of extracellular volume (ECV). T1 mapping is sensitive to myocardial water content of both intra- and extracellular in origin, but the effect of intravascular compartment changes on T1 has been largely n...
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Background Patients with diabetes mellitus (DM) are known to have microvascular coronary artery disease (CAD), in the absence of hypertension and flow limiting stenoses on epicardial coronary arteries. Microvascular coronary dysfunction can be detected on CMR using adenosine stress perfusion imaging. Native T1 values can detect tissue water content of intra/extracellular or intra/extravascular ...
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Cardiac adaptation to high-intensity exercise is well recognized and often termed the athlete’s heart. The characteristic features of athlete’s heart are increased left ventricular (LV) volume, increased LV wall thickness and mass, resting bradycardia, and ECG repolarization abnormalities. These changes are particularly associated with endurance training causing eccentric LV hypertrophy, wherea...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Imaging
سال: 2021
ISSN: 1941-9651,1942-0080
DOI: 10.1161/circimaging.120.011774